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We classify the functional characteristics of currently known paralogs into two distinct groups (Figure 25A): (1) paralogs that have lost metal coordinating residues and may or may not dispense of the need for metal altogether (Category 1), and (2) paralogs that are metal-promiscuous and require a metal for catalysis but may or may not retain function with Zn II (Category 2)

doi: 10.1016/j.mayocp.2013.02.007 8

Understanding your body mass index can be a helpful starting point, but its important to look beyond the number and consider your overall body composition, muscle mass, and health habits for a more complete view of your well-being

This modification typically occurs in proteins rich in lysine, such as histones or myosin